Osteoarthritis (OA) is the most prevalent arthritis worldwide and is characterized by chronic pain and impaired physical function. OA is the joint condition which occurs when there is disruption of the surface cartilage and the underlying bone. Up until recently, it was thought that this condition was caused by mechanical forces that increased joint loading.

Advances in the understanding of cartilage cells(chondrocytes) and the synovial membrane as targets for inflammation suggests that multiple mechanisms especially inflammation are involved leading to the eventual disruption of the joint.

In response to new information, innovative treatments are evolving.

Pain In Osteoarthritis